SPRAGUE, Alfred White, author, born in Honolulu, Sandwich islands, 17 June, 1821. His father, Daniel Chamberlain, was the first missionary to the Sandwich islands in 1819, and built the first frame house there, and his mother was the first white woman to land on those islands. The son was graduated at Amherst in 1847, and in 1849 changed his name to Sprague by an act of the legislature of Massachusetts. In 1854-'5 he was professor of natural philosophy and chemistry in Washington university, St. Louis, and from 1859 till 1863 he was experimental lecturer on these subjects in private schools in Boston. In 1863 he applied theautomatic regulation of heat to the manufacture of nitrous-oxide gas for surgical purposes. Mr. Sprague is the author of lectures entitled "Chemical Experiments" (Boston, 1853); and "Elements of Natural Philosophy" (1856).