TREJO, Hernando de (tray'-ho), Spanish adventurer, born in Truxillo, Estremadura, about 1510; died in Asuncion, Paraguay, in 1555. He served in Italy, went to Mexico about 1540, and in 1550 to La Plata with Juan de Salazar de Espinosa. They encountered heavy seas and hurricanes, and the adventurers became dissatisfied. Dissensions following between the chief pilot and Juan de Sa-lazar, the latter was deposed from the command and Trejo was elected in his place. But the latter, fearing that the adelantado of La Plata would punish him for his rebellion, landed Salazar at San Vicente and sailed to the south, intending to found a settlement. Driven by contrary winds, he landed early in 1551 in a bay a few miles north of Santa Catalina island and south of Cananea. There he founded the city of San Francisco and tried to explore the interior, but the warlike Indians checked his progress and cut off his supplies. The adventurers greatly suffering from want, Trejo determined in 1553 to abandon the colony and set out for Asuncion. Sailing up Itabucu river and otherwise following the route that had been explored a few years before by Cabeza de Vaca, he entered the territory of the Guaranis, where he was assailed by the Indians, but he defeated them and pursued his march toward Asuncion, suffering great hardships and arriving at last in May, 1554, after a march of six months. He was imprisoned there by Martinez de Irala, and, being released by order of the court, was appointed governor of the city, dying a few weeks later. He had married in San Francisco one of the daughters of the deceased adelantado-elect, Sanabria.--Their son, Hernando de Trejo y Sanabria, born in San Francisco in 1553; died in Rio de Janeiro in 1614, became a Franciscan, and is counted among the first apostles of Brazil. He was elected in 1603 provincial of the latter country, and founded colleges and built churches everywhere, interesting himself to the last in the welfare of the Indians, especially of the half-breeds, or Mamalucos, and became their legislator. He left a valuable manuscript, "Arte de la lengua de los Mamalucos," which is preserved in the archives of Simancas.