WISE, Isaac Mayer, clergyman, born in Stein-grub, Bohemia, 3 April, 1819. After following the usual rabbinical training, and a course of secular instruction at Prague, he was graduated at the University of Vienna in 1843. In the same year he was appointed rabbi of Radnitz, Bohemia, where he remained three years. He then went to New York, and from 1846 till 1854 he officiated in Albany. In 1854 Dr. Wise was called to Cincinnati, Ohio, where he has remained. In 1854 he published the weekly, "The Israelite," and in 1855 a German supplement, "Die Deborah." He has also issued a special ritual called "Ninhag America," which has been adopted by a large number of congregations, and he has been an industrious writer on Jewish and polemical topics. He has lectured throughout the country, and consecrated a large number of synagogues, He is identified with the reform movement in American Judaism, and his energy led to the union of American congregations and the Hebrew union college, of which he is president. Among his works are a "History of the Israelitish Nation" (Albany, 1854); "Essence of Judaism" (Cincinnati, 1860) ; "Judaism : its Doctrines and Duties" (1862); "The Martyrdom of Jesus of Nazareth," to prove that the Jews were not responsible for the crucifixion (1874)" "The Cosmic God" (1876): and "History of the Hebrews' Second Commonwealth" (1880).